Thursday, November 30, 2006

Clinic Notes: Autism as a Neurological Disorder vs. Autistic Behavior

Presently we are analyzing data from over 2500 surveys from mothers of children diagnosed with autism and mothers of normally developing children. The survey, which can be found at http://www.ABA4Autism.com, has a variety of pre and post-natal questions. In the biographical portion of the survey we ask mothers to give us their child's diagnosis. We thought we would get several different diagnostic labels such as autism, PDD-NOS, or Asperger's. Instead we have so many diagnostic labels that we are not sure how to proceed. We have many comorbid diagnoses such as Down's syndrome and autism, Fragile X syndrome and autism, Autism Spectrum Disorder, with and without comorbid disorders, and countless more. Physicians or psychologist made all of these diagnoses. There are many problems in diagnosing autism and I certainly don't have the answer for all of the problems. But I think much of the confusion is caused by professionals who talk of atism as a neurological disorder and professionals, sometime the same professionals, who talk about autistic behaviors such as self-stim, OCD, sensory issues, etc. These "autistic behaviors" can be seen in a wide variety of neurological disorders. Before we can do definitive research in autism we need to be clear on what we are talking about when we make a diagnosis.

Wednesday, November 22, 2006

Clinic Notes: The Combating Autism Act

According to a recent note in the Schafer Report funding for investigating the role of environmental factors as a possible cause of autism has been removed in the House by Energy and Commerce Chair Joe Barton. The Senate has already voted 100 to 0 to fund special centers that would focus on the role of environmental factors as possible cause of autism. I don't know how this will all turn out in this lame duck congress. Last summer the Senate voted to exclude money that would look into vaccines containing thimerosal as a possible cause of autism. So both houses are trying to play to special interest and hogtie science. But science doesn't work that way. I have no idea whether thimerosal or environmental factors are involved in autism. We are now analyzing data from over 2500 surveys from mothers of children with autism and normally developing children and we will look at what we damn well want to. And the rest of the scientific community should do the same. Many in Congress have already demonstrated that they are cntrolled by special interest and are not concerned with finding a cure for autism. Science should find away to do the research without government funding.Schafer Autism Report Nov. 20, 2006

Sunday, November 19, 2006

Clinic Notes: Mercury and Autism

In 1971, Iraq was given 90,000 metric tons of wheat seed by the United States. The seed was supposed to be planted by the Iraqis and had been treated with the fungicide methylmercury. Unfortunately, the Iraqis ground the seed and baked it into bread. Six thousand people were hospitalized with mercury poisoning and 450 died. Pregnant women gave birth to children with mental retardation, seizures, and other birth defects. The number of children, if any, who developed autism, is unknown. Without question mercury causes brain damage in children and adults. And like other poisons size matters. The same dose can be 100 times more harmful in a child than an adult. Mercury is now a part of our environment. Common products such as tuna fish, as well as other fish, and many vaccines other than the MMR vaccine contain mercury. Mercury is also a byproduct of industry. The question is how much mercury can the body tolerate without damage. We have some guidance, such as eating fish no more than 2-3 times per week. But supposed you eat fish 2-3 times per week and also live in an area contaminated with mercury because of industrial pollution? The EPA estimates that 1 woman in 5 during their childbearing years have mercury levels in their blood that exceed EPA safety guidelines. Perhaps we should be worrying more about mercury levels in the environment and not just confine our worries to vaccines.

For more information read the article by Lidia Wasowicz http://tinyurl.com/y4k46t

Wednesday, November 15, 2006

Clinic Notes: Blaming Moms Blaming Dads for Autism

In the 1940's, after Leo Kanner had described autism in children, psychoanalyst Bruno Bettelheim wrote extensively about the causal relationship between emotionally distant mothers (refrigerator mothers) and their autistic children. Of course, you can imagine the guilt this caused moms. Now maybe it's dad's turn. A recent study by epidemiologist Avi Reichenberg of the Mt. Sinai School of Medicine found that dads older than forty were six times more likely to have children diagnosed with autism than younger dads. Theoretically, the DNA in the older sperm has decayed.

(See James Ottar Grundvig for The Epoch Times at
http://www.theepochtimes.com/news/6-11-13/48039.html)

Wednesday, November 08, 2006

Clinic Notes: The CDC's Proposed Autism Study

The Center for Disease Control and Prevention (CDC) announced a large-scale study that will look for pre and postnatal causes of autism. The $7.8 million dollar study will be conducted in 5 or 6 states and is the largest federally autism study to date. The press release said that the study would include as many as 2700 hundred children. Their sample includes both children with autism and normally developing children. For $7.8 million dollars I would expect a larger sample. We are now analyzing data on more than 2000 children with autism and normally developing children and even if we include our faculty salaries we are well under a $150,00 and we are not working on the study full time. I hope the autism community gets what they are paying for.
http://www.edweek.org/ew/articles/2006/11/08/11health-1.h26.html

Thursday, November 02, 2006

Clinic Notes: Mirror Neurons and ABA

If I am shopping with my wife and I see her pick up a man's shirt and smile and look at me I not only observe her behavior I know her intentions. Furthermore, we could monitor my wife's brain activity and see which neurons were involved in her behavior. The interesting thing here is that if we also monitored my brain activity as I observed my wife's behavior the same neurons would be firing in my brain. These so-called mirror neurons in my brain are thought to be templates for specific behaviors. One hypothesis suggests that mirror neurons do not function in children with autism and cause social problems. If this is true then how might we use ABA to improve mirror neuron functioning in children with autism? I would suggest a first step would be to teach children with autism to model behavior in a normally developing peer. Once the child with autism is modeling the behavior we would then ask the child with autism questions about the peer's behavior and itentions. No doubt we would have to use verbal prompts to establish the correct intention to the modeled behavior. Hopefully, with repetition we could set up circuits of functioning mirror neurons in the child with autism. In my clinic I am exploring this and we will see what happens.